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Alat rapid antigen: why do some people never get the new coronavirus?

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Alat rapid antigen: why do some people never get the new coronavirus?

The French newspaper Le Figaro said a small number of people were less likely to be infected than others, despite having been in contact with someone infected with the new coronavirus, due to a very specific set of factors.

Eloise, 25, who has never contracted the disease (pseudonym), said in her report published in the paper, in her surprise, "I have been exposed to many times. This disease, my friend got it last summer, and I didn't care about it at all." Her father, who lived in the same house with his wife and two infected children, also survived.

The lucky girl didn't understand why she and her father didn't have the virus. "We all get tested regularly. Last July, the serology was negative. We were vaccinated and we were careful with the disease, but that's about it."

The paper asked why some people have never been infected with the new coronavirus and will not contract it, despite the continuing rise in the Omicron wave and with France recording nearly half a million positive cases in 24 hours? Note that, like other diseases, the new coronavirus has factors that increase its risk of reproduction, but also factors that reduce it.

"Some epidemiologists are trying to understand why some people have not been infected with the new coronavirus from arapid influenza b ag - UDXBIO biological and morphological perspective," including blood type, said Philippe Amuel, a professor of public health. He pointed out that people with blood type O are generally considered to have a lower risk of contracting the new coronavirus by about 20%, while people with blood types A and AB have a higher risk of contracting the new coronavirus, said Jacques, director of research at the Institute of Health and Medical Research at the University of Nantes. Lopando thinks so too.

The researcher collected dozens of studies published in this direction since the beginning of the outbreak. He pointed out that blood type also has an impact on the outcome of exposure to the new coronavirus at other levels, with people with blood type O being more resistant to developing severe symptoms.

The effectiveness of the immune system is another factor in reducing the risk of infection, and it varies from person to person. "Because of pre-existing immunity, some people have a lower chance of contracting Covid-19 than others," says Philip Amuel. Infection with the group A viruses that cause colds can confer immunity to B Immunity of the new coronavirus group.

In the study, the researchers concluded that colds can allow the body to make T cells that can more quickly respond to SARS-CoV-2, the new coronavirus that causes Covid-19, a finding that could constitute a new way to develop new The basis of the vaccine is to enable T cells to provide a longer-lasting antibody response, unlike current vaccines that target the spike protein, which tends to mutate easily and lose its effectiveness.

In addition to blood type and immunity, there is another genetic factor that reduces the risk of infection. Numerous studies have shown that genes play an important role in preventing severe symptoms after infection with the new coronavirus. John-François Deleuze, director of the National Center for Human Genome Research, said: "There are many reasons to believe that we are more or less susceptible to infection due to the level of fusion between the virus and the receptor. At the genetic level , we can imagine very specific differences in identifying the virus that might prevent it from entering."

However, conducting research to elucidate these properties would require exposing some people who have never been infected with the new coronavirus, exposing them to the virus, and then measuring their antibody levels to look for genetic differences, but knowing whether a person has the virus is very difficult, especially It's the vaccination that gives the vast majority of people antibodies, and it's hard to imagine people voluntarily exposing them to the new coronavirus.