Views: 0 Author: Site Editor Publish Time: 2023-05-05 Origin: Site
The AbC-19 Rapid Antibody Test is an immunological test for COVID-19 exposure.Rapid Testing uses a lateral flow test to determine whether a person has IgG antibodies against the SARS-CoV-2 virus that causes COVID-19.The test uses a drop of blood from a finger prick and provides results within 20 minutes.The test has a sensitivity of 98.03% and a specificity of 99.56%.The test is paired with an easy-to-use mobile app that allows trained professionals to generate antibody test certificates for storage on a person's smartphone.
The lateral flow test (LFT) is an assay also known as a lateral flow device (LFD), lateral flow immunochromatographic assay, or rapid test.It is a simple device designed to detect the presence of target substances in liquid samples without the need for specialized and expensive equipment.LFTs are widely used for medical diagnostics in the home, point-of-care, and laboratory.For example, a home pregnancy test is an LFT that detects specific hormones.These tests are simple and affordable, and usually show results in about five to thirty minutes.Many laboratory-based applications increase the sensitivity of simple LFTs by using additional specialized equipment.Since the target substance is usually a biological antigen, many lateral flow tests are rapid antigen tests (RAT or ART).LFT operates on the same principle as affinity chromatography in an enzyme-linked immunosorbent assay (ELISA).Essentially, these tests run a liquid sample along the surface of the pad with reactive molecules, showing a visually positive or negative result.These pads are based on a series of capillary beds such as porous paper sheets,microstructured polymers or sintered polymers.Each of these pads has the ability to spontaneously transport fluids (e.g. urine, blood, saliva).
The sample pad acts as a sponge and holds excess sample fluid.After soaking, the liquid flows to a second conjugate pad, where the manufacturer stores freeze-dried bioactive particles called conjugates in a salt-sugar matrix.The conjugate pad contains all the reagents needed to optimize the chemical reaction between the target molecule (e.g. antigen) and its chemical partner immobilized on the particle surface (e.g. antibody).This marks the particles of interest as they pass through the pad and continue across the test and control lines.The test line shows a signal, usually the color in a pregnancy test.The control line contains the affinity ligand and shows whether the sample is flowing through and the biomolecules in the conjugated pad are active.After passing through these reaction zones the fluid enters the final porous material, the wick, which simply acts as a waste container.LFT can be performed as a competition or sandwich assay.
